News & Publications

1. Optimised nickase- and nuclease-based prime editing in human and mouse cells. https://academic.oup.com/nar/article/49/18/10785/6371974 

2. Large deletions induced by Cas9 cleavage. https://www.nature.com/articles/s41586-018-0380-z 

3. Targeted deletion of an entire chromosome using CRISPR/Cas9. https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(17)30257-5 

4. Versatile single-step-assembly CRISPR/Cas9 vectors for dual gRNA expression. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187236 

5. CRISPR applications for Duchenne muscular dystrophy: from animal models to potential therapies. https://wires.onlinelibrary.wiley.com/doi/full/10.1002/wsbm.1580 

6. Expanding the RNA-Guided Endonuclease Toolkit for Mouse Genome Editing. https://www.liebertpub.com/doi/abs/10.1089/crispr.2018.0050 

7. CRISPR-mediated megabase-scale transgene de-duplication to generate a functional single-copy full-length humanised DMD mouse model. https://link.springer.com/article/10.1186/s12915-024-02008-7 

8. Optimal SpCas9- and SaCas9-mediated gene editing by enhancing gRNA transcript levels through scaffold poly-T tract reduction. https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-025-11317-2 

9. CRISPR-mediated generation and comprehensive phenotyping of Duchenne Muscular Dystrophy mouse models. https://link.springer.com/article/10.1186/s44330-024-00019-y